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Auflistung nach Autor:in "Luz, Hannes"

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  • Konferenzbeitrag
    Family specific rates of protein evolution
    (German Conference on Bioinformatics 2005 (GCB 2005), 2005) Luz, Hannes; Vingron, Martin
    Amino acid changing mutations in proteins are contstrained by purifying selection and accumulate at different rates. We estimate evolutionary rates on multiple alignments of eukaryotic protein families in a maximum likelihood framework. We find that the evolution of indispensable proteins is constrained by selection and that protein secretion is coupled to an increased evolutionary rate.