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Auflistung nach Schlagwort "evolutionary algorithm"

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  • Textdokument
    Evolutionary algorithms for finding gen knockout targets
    (INFORMATIK 2017, 2017) Jähne, Paul
    The organic chemical industry is primarily based on fossil raw materials. An alternative is the use of industrial biotechnology which is based on microorganisms that produce the needed substances as a part of their metabolism from renewable raw materials. Metabolic engineering is a technique to increase the production of the desired products through genetic modifications. The needed modifications are not trivial and no algorithm is currently known. Therefore this paper investigates the use of evolutionary algorithms for finding genetic modifications. The production of polyhydroxybutyrate out of methanol by Methylobacterium extorquens AM1 is examined as an example. The proposed evolutionary algorithm is able to find a modification with 15 knockouts that increases the production of polyhydroxybutyrate by a factor of 294 at 0.6-fold biomass growth rate.
  • Textdokument
    A meta-heuristic for access control test data creation in access control model testing
    (Open Identity Summit 2017, 2017) Winterstetter, Matthias; Kurowski, Sebastian
    User to Document Access data is in most cases protected and as such difficult to acquire for research purposes. This work seeks to circumvent this problem by creating research data on the basis of reference processes through the evolutionary Algorithm. Data created through this method, while not as accurate as real data, still has it’s foundation in reality through the reference process and can as such be used as a replacement.