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Family specific rates of protein evolution

Author:
Luz, Hannes [DBLP] ;
Vingron, Martin [DBLP]
Abstract
Amino acid changing mutations in proteins are contstrained by purifying selection and accumulate at different rates. We estimate evolutionary rates on multiple alignments of eukaryotic protein families in a maximum likelihood framework. We find that the evolution of indispensable proteins is constrained by selection and that protein secretion is coupled to an increased evolutionary rate.
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Luz, H. & Vingron, M., (2005). Family specific rates of protein evolution. In: Torda, A., Kurtz, S. & Rarey, M. (Hrsg.), German Conference on Bioinformatics 2005 (GCB 2005). Bonn: Gesellschaft für Informatik e.V.. (S. 133-144).
@inproceedings{mci/Luz2005,
author = {Luz, Hannes AND Vingron, Martin},
title = {Family specific rates of protein evolution},
booktitle = {German Conference on Bioinformatics 2005 (GCB 2005)},
year = {2005},
editor = {Torda, Andrew AND Kurtz, Stefan AND Rarey, Matthias} ,
pages = { 133-144 },
publisher = {Gesellschaft für Informatik e.V.},
address = {Bonn}
}
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More Info

ISBN: 3-88579-400-4
ISSN: 1617-5468
xmlui.MetaDataDisplay.field.date: 2005
Language: en (en)
Content Type: Text/Conference Paper
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Gesellschaft für Informatik e.V. (GI), Kontakt: Geschäftsstelle der GI
Diese Digital Library basiert auf DSpace.

 

 


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Gesellschaft für Informatik e.V. (GI), Kontakt: Geschäftsstelle der GI
Diese Digital Library basiert auf DSpace.