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Memory efficient folding algorithms for circular RNA secondary structures

Author:
Hofacker, Ivo L. [DBLP] ;
Stadler, Peter F. [DBLP]
Abstract
A small class of RNA molecules, in particular the tiny genomes of viroids, are circular. Yet most structure prediction algorithms handle only linear RNAs. The most straightforward approach is to compute circular structures from "internal" and "external" substructures separated by a base pair. This is incompatible, however, with the memory-saving approach of the Vienna RNA Package which builds a linear RNA structure from shorter (internal) structures only. Here we describe how circular secondary structures can be obtained without additional memory requirements as a kind of "post-processing" of the linear structures.
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Hofacker, I. L. & Stadler, P. F., (2005). Memory efficient folding algorithms for circular RNA secondary structures. In: Torda, A., Kurtz, S. & Rarey, M. (Hrsg.), German Conference on Bioinformatics 2005 (GCB 2005). Bonn: Gesellschaft für Informatik e.V.. (S. 15-25).
@inproceedings{mci/Hofacker2005,
author = {Hofacker, Ivo L. AND Stadler, Peter F.},
title = {Memory efficient folding algorithms for circular RNA secondary structures},
booktitle = {German Conference on Bioinformatics 2005 (GCB 2005)},
year = {2005},
editor = {Torda, Andrew AND Kurtz, Stefan AND Rarey, Matthias} ,
pages = { 15-25 },
publisher = {Gesellschaft für Informatik e.V.},
address = {Bonn}
}
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More Info

ISBN: 3-88579-400-4
ISSN: 1617-5468
xmlui.MetaDataDisplay.field.date: 2005
Language: en (en)
Content Type: Text/Conference Paper
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Gesellschaft für Informatik e.V. (GI), Kontakt: Geschäftsstelle der GI
Diese Digital Library basiert auf DSpace.