Comparison of centralities for biological networks
ISSN der Zeitschrift
German Conference on Bioinformatics 2004, GCB 2004
Regular Research Papers
Gesellschaft für Informatik e.V.
The analysis of biological networks involves the evaluation of the vertices within the connection structure of the network. To support this analysis we discuss five centrality measures and demonstrate their applicability on two example networks, a protein-protein-interaction network and a transcriptional regulation network. We show that all five centrality measures result in different valuations of the vertices and that for the analysis of biological networks all five measures are of interest.