Tanimoto’s Best Barbecue: Discovering Regulatory Modules using Tanimoto Scores
| dc.contributor.author | Menzel, Peter | |
| dc.contributor.author | Stadler, Peter F. | |
| dc.contributor.author | Mosig, Axel | |
| dc.contributor.editor | Falter, Claudia | |
| dc.contributor.editor | Schliep, Alexander | |
| dc.contributor.editor | Selbig, Joachim | |
| dc.contributor.editor | Vingron, Martin | |
| dc.contributor.editor | Walther, Dirk | |
| dc.date.accessioned | 2019-05-15T08:32:33Z | |
| dc.date.available | 2019-05-15T08:32:33Z | |
| dc.date.issued | 2007 | |
| dc.description.abstract | We present a combinatorial method for discovering cis-regulatory modules in promoter sequences. Our approach combines “sliding window” approaches with a scoring function based on the so-called Tanimoto score. This allows to identify sets of binding sites that tend to occur preferentially in the vicinity of each other in a given set of promoter sequences belonging to co-expressed or orthologous genes. We bench- mark our method on a data set derived from muscle-specific genes, demonstrating that our approach is capable of identifying modules that were identified as functional in previous studies. | en |
| dc.identifier.isbn | 978-3-88579-209-3 | |
| dc.identifier.pissn | 1617-5468 | |
| dc.identifier.uri | https://dl.gi.de/handle/20.500.12116/22375 | |
| dc.language.iso | en | |
| dc.publisher | Gesellschaft für Informatik e. V. | |
| dc.relation.ispartof | German conference on bioinformatics – GCB 2007 | |
| dc.relation.ispartofseries | Lecture Notes in Informatics (LNI) - Proceedings, Volume P-115 | |
| dc.title | Tanimoto’s Best Barbecue: Discovering Regulatory Modules using Tanimoto Scores | en |
| dc.type | Text/Conference Paper | |
| gi.citation.endPage | 77 | |
| gi.citation.publisherPlace | Bonn | |
| gi.citation.startPage | 68 | |
| gi.conference.date | September 26-28, 2007, Potsdam, | |
| gi.conference.location | Potsdam | |
| gi.conference.sessiontitle | Regular Research Papers |
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