Family specific rates of protein evolution

dc.contributor.author	Luz, Hannes
dc.contributor.author	Vingron, Martin
dc.contributor.editor	Torda, Andrew
dc.contributor.editor	Kurtz, Stefan
dc.contributor.editor	Rarey, Matthias
dc.date.accessioned	2019-08-27T08:22:35Z
dc.date.available	2019-08-27T08:22:35Z
dc.date.issued	2005
dc.description.abstract	Amino acid changing mutations in proteins are contstrained by purifying selection and accumulate at different rates. We estimate evolutionary rates on multiple alignments of eukaryotic protein families in a maximum likelihood framework. We find that the evolution of indispensable proteins is constrained by selection and that protein secretion is coupled to an increased evolutionary rate.	en
dc.identifier.isbn	3-88579-400-4
dc.identifier.pissn	1617-5468
dc.identifier.uri	https://dl.gi.de/handle/20.500.12116/24927
dc.language.iso	en
dc.publisher	Gesellschaft für Informatik e.V.
dc.relation.ispartof	German Conference on Bioinformatics 2005 (GCB 2005)
dc.relation.ispartofseries	Lecture Notes in Informatics (LNI) - Proceedings, Volume P-71
dc.title	Family specific rates of protein evolution	en
dc.type	Text/Conference Paper
gi.citation.endPage	144
gi.citation.publisherPlace	Bonn
gi.citation.startPage	133
gi.conference.date	5.-7. Oktober 2005
gi.conference.location	Hamburg
gi.conference.sessiontitle	Regular Research Papers

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