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Considerations of graph-based concepts to manage of computational biology models and associated simulations

dc.contributor.authorHenkel, Ron
dc.contributor.authorNovère, Nicolas Le
dc.contributor.authorWolkenhauer, Olaf
dc.contributor.authorWaltemath, Dagmar
dc.contributor.editorGoltz, Ursula
dc.contributor.editorMagnor, Marcus
dc.contributor.editorAppelrath, Hans-Jürgen
dc.contributor.editorMatthies, Herbert K.
dc.contributor.editorBalke, Wolf-Tilo
dc.contributor.editorWolf, Lars
dc.date.accessioned2018-11-06T10:57:32Z
dc.date.available2018-11-06T10:57:32Z
dc.date.issued2012
dc.description.abstractOver the past years various databases in Life Sciences have been developed, among them databases to handle computational models of biological systems. Exchange formats that represent these models are typically XML- based; they encode models as networks. Models are published together with supplementary materials such as annotations, simulation experiment descriptions, or result sets. In consequence, not only model files need to be managed, but also the associated simulation setups, and highly linked meta-information. We discuss here the use of graph databases for model storage as they well reflect this interrelated nature. They can also enhance the integrated management of computational models and associated meta-information, as they handle connections between models, simulation descriptions and result data files, as well as external knowledge. This property enhances version control, retrieval and ranking, thereby resulting in improved model reuse and result reproducibility.en
dc.identifier.isbn978-3-88579-602-2
dc.identifier.pissn1617-5468
dc.identifier.urihttps://dl.gi.de/handle/20.500.12116/17789
dc.language.isoen
dc.publisherGesellschaft für Informatik e.V.
dc.relation.ispartofINFORMATIK 2012
dc.relation.ispartofseriesLecture Notes in Informatics (LNI) - Proceedings, Volume P-208
dc.titleConsiderations of graph-based concepts to manage of computational biology models and associated simulationsen
dc.typeText/Conference Paper
gi.citation.endPage1551
gi.citation.publisherPlaceBonn
gi.citation.startPage1545
gi.conference.date16.-21. September 2012
gi.conference.locationBraunschweig
gi.conference.sessiontitleRegular Research Papers

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