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Identification and measurement of neigbor dependent nucleotide substitution processes

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dc.contributor.authorArndt, Peter F.
dc.contributor.editorGiegerich, Robert
dc.contributor.editorStoye, Jens
dc.date.accessioned2019-10-11T11:32:40Z
dc.date.available2019-10-11T11:32:40Z
dc.date.issued2004
dc.description.abstractThe presence of different neighbor dependent substitution processes generates specific patterns of dinucleotide frequencies in all organisms. Based on a general framework of how to include such processes into more realistic models of nucleotide substitutions we develop a method that is able to identify such processes, measure their strength, and judge their importance to be included into the modeling. Starting from a model for neighbor independent nucleotide substitution we successively add neighbor dependent substitution processes in the order of their ability to increase the likelihood of the model describing the data. The analysis of neighbor dependent nucleotide substitutions in human, zebrafish and fruit fly is presented.en
dc.identifier.isbn3-88579-382-2
dc.identifier.pissn1617-5468
dc.identifier.urihttps://dl.gi.de/handle/20.500.12116/28670
dc.language.isoen
dc.publisherGesellschaft für Informatik e.V.
dc.relation.ispartofGerman Conference on Bioinformatics 2004, GCB 2004
dc.relation.ispartofseriesLecture Notes in Informatics (LNI) - Proceedings, Volume P-53
dc.titleIdentification and measurement of neigbor dependent nucleotide substitution processesen
dc.typeText/Conference Paper
gi.citation.endPage234
gi.citation.publisherPlaceBonn
gi.citation.startPage227
gi.conference.dateOctober 4-6, 2004
gi.conference.locationBielefeld
gi.conference.sessiontitleRegular Research Papers

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P053 - GCB 2004 - German Conference on Bioinformatics